UPfront heat-shock proteins key to controlling inflammation attractive design HotSpring World is giving away a 30-piece BBQ set to help put a sizzle into your summer socialising with family and friends. Dining al fresco is great fun and HotSpring World knows a thing or two about boosting mood and wellbeing with its home spas. To see the range of spas, visit hotspringworld.co.uk To stand a chance of winning the BBQ set, send your name and address to Inspire HotSpring World Competition, CPL, 1 Cambridge Technopark, Cambridge, CB5 8PB by 28 July 2017. W in ! Three University of Sheffield graduates are helping people with arthritis and other musculoskeletal conditions who may find fastening buttons a challenge. design Council Spark programme winners Matt Barrett, natalie English and Tom Fantham have been awarded 25,000 by arthritis Research UK, to develop their Handy Fasteners magnetic buttons, which can be retrofitted to any garment. Barrett, an aerospace graduate, is enjoying the unexpected direction his engineering career has taken: Its been a weird, but hugely exciting journey. The product development process has been really interesting and the look on peoples faces when they try out the shirts is amazing. To take a look at the Handy Fasteners video, click here Permanent relief from inflammation caused by autoimmune conditions including rheumatoid and psoriatic arthritis could be offered by heatshock protein therapies. Current treatments dampen down inflammation, but this is rarely permanent. Regulatory T cells (Tregs) which control the immune system could be a focus for future study, according to a review article in the journal Rheumatology (February 2017). Heat-shock proteins, present in all cells, are activated during inflammation and these are recognised by Tregs. Animal studies and clinical trials have demonstrated that heat-shock proteins have a protective effect in inflammatory arthritis. However, further work is needed to assess the safety and long-term effectiveness of specific heat-shock protein therapies, and whether they can be used alongside current treatments. Move in the right direction A new active shoe, which aims to reduce damaging impact on joints, has been designed for women with swollen feet. In tests, the Move shoe was shown to deliver 23-25 per cent less impact shock to the lower leg than other leadingbrand trainers. Created by Cosyfeet, it has an EEEEE+ fitting as standard, a cushioned footbed, and a lightweight, super-flexible sole that moves with the natural motion of your foot. A padded tongue cushions your instep as you walk, while a deep, seam-free toe box protects sensitive digits. There is also a soft, yielding collar around the ankle. Priced at 69, the Move shoe comes in sizes four to nine including half sizes and is available in dove grey, jeans blue or navy. For more details, visit cosyfeet.com or call 01458 447275.